Tablet Presentation

Each tablet contains:
Ivermectin USP 12 mg

Ivermectin belongs to anthelmintic class and is used to treat onchocerciasis. This infection is caused by the roundworm and leads to certain symptoms such as rashes, bumps under the skin and blindness or vision loss. It is applied on skin for external infections.

Indications & Usage

• Head & pubic lice infection
• Scabies
• Onchocerciasis
• Strongyloidiasis
• Wuchereria bancrofti infection

Mechanism of Action

Ivermectin binds to the glutamate- gated chloride channel ion channels in the nerve cells of the microflora thus binding causes an increase in permeability of the cell membrane of the microbe which leads to hyperpolarization and therefore paralysis and death of the parasite.

Pharmacokinetics

Absorption: It is absorbed from gastrointestinal tract
Protein Binding: It is 93% bound to proteins
Metabolism: It is metabolized in the liver
Excretion: It is excreted via urine and through feces

Side Effects

• Dizziness
• Nausea
• Vomiting
• Pain in stomach
• Constipation
• Discomfort in chest
• Sleepiness
• Weakness
• Loss of appetite

Contraindications

• Contraindicated in liver diseases
• Contraindicated during pregnancy
• Contraindicated in asthma

Drug Interactions

• Acetaminophen
• Aspirin
• Albendazole
• Diphenhydramine
• Aspirin
• Prednisone
• Ascorbic acid
• Valproic acid

Storage

Store it at room temperature

Precaution

Ask your doctor before using when you are planning to be pregnant. Stop using it if it causes allergy.